Therapeutics

Latest Innovations

Compounds for the Treatment of Fluoquinolone resistant infections

 

Researchers from the University of Illinois have synthesized a variety of compounds with strong activity toward fluoroquinolone resistant bacteria. These compounds...

Peptide Based Inhibitor of Calcium Current

 

This technology is a short fragment of a naturally occurring peptide that can be used to regulate the density of calcium current in mammalian cells. Modulation of...

Powerful Biphosophonates for Treatment of Cancer, Bone Loss, and Infectious Disease

 

Although there are already a few existing compounds for use in the treatment of bone diseases, these new compounds may have efficacy exceeding that of current...

New Drugs for Malarial and Bacterial Infections

 

New anti-infectives are required now more than ever as resistance to existing drugs increases in prevalence. Enzymes unique to bacteria or parasites are potential...

Supramolecular Assembly for Non-Viral Gene Delivery

 

Gene therapy is an approach for human disease treatment. This is done by inserting nucleic acids into cells to produce proteins, fix or replace damaged genes, and...

Electronic Tuning Of Site Selectivity For Complex Molecule Synthesis

 

Researchers from the University of Illinois have developed a method for selectively derivatizing complex natural molecules such as Amphotericin B. The technology...

Antibacterial Drug Targeting Isoprenoid Biosynthesis

 

Researchers at the University of Illinois and the University of California at San Diego have developed a variety of potential inhibitors of Isoprenoid biosynthesis...

Less Toxic Amphotericin B Derivative

 

Researchers at the University of Illinois have developed a derivative of Amphotericin B that likely has a lower toxicity than the popular fungicide. The derivative...

Ionic Helical Polypeptides - Non-Viral Gene Delivery with Improved Transfection Efficiency

 

Tremendous potential exists for helical polypeptides that are water soluble (ionic) and remain stable at physiological conditions,...

Algorithm Modified Deoxynybomycin for the Treatment of Gram-Negative Bacteria

Dr. Hergenrother from the University of IL has developed a novel antibiotic that is effective against certain antibiotic-resistant gram-negative bacteria. His powerful...

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