Drug Delivery

Latest Innovations

Preparation of Degradable Silica-Drug Conjugated Nanoparticle with Monodisperse Particle Sizes

 

The invention provides a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to...

A More Stable and Efficient Retroviral Gene Delivery Vector

 

This technology is a viral vector based on the murine leukemia virus (MLV), which has been favored for clinical gene therapy due to its preferential infectivity of...

Cell Encapsulation in Uniform Microcapsules with Built-In Cell Centering Mechanism

 

A system that incorporates teachings of the present disclosure may include, for example, an apparatus having an outer nozzle operable to discharge an outer stream...

Controlled Targets-Specific Drug Delivery via DNAzyme (aptazyme or aptamer) - Functionalized Liposome

 

An amphiphilic substance includes a hydrophobic group, and a polynucleotide group attached to the hydrophobic group. The polynucleotide group includes a first...

Ionic Helical Polypeptides - Non-Viral Gene Delivery with Improved Transfection Efficiency

 

Tremendous potential exists for helical polypeptides that are water soluble (ionic) and remain stable at physiological conditions,...

Bio-Engineered Hyper-Functional Super Helicases

 

 

Dr. Taekjip Ha has developed a bio-engineered, hyper-functional "super" helicase that is capable of unwinding 5000+ base pairs without stopping. The super...

Multiplexed Targeted Genome Engineering and Gene Activation

 

 

Dr. Pablo Perez-Pinera from the University of Illinois has developed a multiplexable and universal nuclease-assisted...

A Sustained Inhibition of Cancer Stem Cells via STAT-3 Modulation

 

 

Dr. Dipanjan Pan from the University of Illinois has...

Solution Coating and Printing of Pharmaceutical Nanothin Films and Multilayer Nanocomposites

A meniscus-guided solution coating technique to produce pharmaceutical nanothin films. This is a new way to manufacture personalized multilayer combination drugs, which...

Long-Release Hydrogel Nanoparticle Carriers for Drug Delivery

Profs. Hyungsoo Choi and Kevin Kim have developed a hydrogel nanoparticle carrier comprising gelatin covalently crosslinked with cyclodextrin, which has a longer drug...

Pages