Drug Delivery

Latest Innovations

Controlled Targets-Specific Drug Delivery via DNAzyme (aptazyme or aptamer) - Functionalized Liposome

 

An amphiphilic substance includes a hydrophobic group, and a polynucleotide group attached to the hydrophobic group. The polynucleotide group includes a first...

Cell Encapsulation in Uniform Microcapsules with Built-In Cell Centering Mechanism

 

A system that incorporates teachings of the present disclosure may include, for example, an apparatus having an outer nozzle operable to discharge an outer stream...

Preparation of Degradable Silica-Drug Conjugated Nanoparticle with Monodisperse Particle Sizes

 

The invention provides a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to...

A More Stable and Efficient Retroviral Gene Delivery Vector

 

This technology is a viral vector based on the murine leukemia virus (MLV), which has been favored for clinical gene therapy due to its preferential infectivity of...

Ionic Helical Polypeptides - Non-Viral Gene Delivery with Improved Transfection Efficiency

 

Tremendous potential exists for helical polypeptides that are water soluble (ionic) and remain stable at physiological conditions,...

Bio-Engineered Hyper-Functional Super Helicases

 

 

Dr. Taekjip Ha has developed a bio-engineered, hyper-functional "super" helicase that is capable of unwinding 5000+ base pairs without stopping. The super...

Multiplexed Targeted Genome Engineering and Gene Activation

 

 

Dr. Pablo Perez-Pinera from the University of Illinois has developed a multiplexable and universal nuclease-assisted...

A Sustained Inhibition of Cancer Stem Cells via STAT-3 Modulation

 

 

Dr. Dipanjan Pan from the University of Illinois has...

Nanomaterial for Active Release of Molecules in Response to Increase in Internal Pressure 

Dr. Hyunjoon Kong from the University of IL has developed a MnO2 based nanosheets complexed with alginate encapsulated in PLGA. This formulation can be used for active...

Solution Coating and Printing of Pharmaceutical Nanothin Films and Multilayer Nanocomposites

A meniscus-guided solution coating technique to produce pharmaceutical nanothin films. This is a new way to manufacture personalized multilayer combination drugs, which...

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