Dr. John Rogers from the University of Illinois at Urbana-Champaign has developed bioresorbable silicon electronics that can be used for real-time sensing of neural electrical activity. This invention could prevent follow-up neural surgeries, and has potentials for long-term monitoring of patients.
Dr. Andrew Smith from the University of Illinois has developed new quantum dots with a multidentate polymer coating that minimizes size while maintaining stability and improving efficiency of conjugation. Quantum dots are promising agents for cellular and molecular imaging, but their bulky organic coatings have limited their use in cells. Dr. Smith's quantum dots are small, stable, and can be conjugated to targeting molecules and purified easily.
Dr. Hergenrother from the University of IL has developed a novel antibiotic that is effective against certain antibiotic-resistant gram-negative bacteria. His powerful predictive algorithm determines accumulation of molecules in Gram-negative bacteria and enables conversion of known Gram-positive only antibiotics into novel compounds with Gram-negative potency.
Dr. Morrissey from the University of IL has developed a novel assay for quantifying polyP levels in patient plasma. This assay allows for polyP quantitation to be performed quickly and in a clinical setting without purification of polyP from plasma. It uses widely available coagulometer. Accurate quantification of circulating polyP levels in a patient's blood will give insight into potential risk of thrombotic and inflammatory diseases. In addition, polyP levels may be significant in conditions such as cancer, sepsis, and trauma-induced coagulopathy.