Dr. Aksimentiev from the University of Illinois at Urbana-Champaign and researchers at TU Delft in The Netherlands have developed a plasmonic nanopore technology for DNA...
Dr. Aksimentiev from the University of Illinois at Urbana-Champaign and researchers at TU Delft in The Netherlands have developed a plasmonic nanopore technology for DNA sequencing. One of the hurdles facing current nanopore-based DNA sequencing technologies is the inability to control DNA speeds passing through the pore. The group has developed nano-antennas that can focus high intensity light on the nanopore to create a "hot-spot" to trap and slow down DNA movement, which can help read long lengths of DNA more efficiently.
Dr. Aksimentiev has developed a new solid-state nanopore DNA sequencing method that affords superior control over DNA translocation. By creating custom-sized nanopores and...
Dr. Aksimentiev has developed a new solid-state nanopore DNA sequencing method that affords superior control over DNA translocation. By creating custom-sized nanopores and exercising specifically designed microfluidic flow, this method allows for "flossing" of a DNA or RNA strand between nanopores. This allows for multiple reads and improved accuracy of sequencing strands. In comparison to existing platforms, this technology offers superior control over the passage of DNA through the nanopore and improves the accuracy of nanopore sequencing results. This technology can be integrated with most existing nanopore sequencing platforms. In addition to DNA, this technology has potential utility for characterizing other biopolymers, including proteins.
