Disease Type

Latest Innovations

Enhancement of Immune Response to Porcine Reproductive and Respiratory Syndrome (PRRS) Vaccine by Interferon Alpha

 

Porcine reproductive and respiratory syndrome (PRRS) is a major problem for hog farmers worldwide. PRRS is caused by a virus which leads to reproductive failure in...

Therapeutic Scheme for Human Basigin

 

Cancer researchers are focusing their efforts on identifying central pathways that trigger or enhance the invasiveness of tumor cells. One such target is EMMPRIN (...

A DNA-Based Diagnostic Test for the Identification of Individuals having the Mutation causing the Ectodermal Dysplasia (ED) Genetic Defect in Sheep

 

Researchers from the University of Illinois have identified a new inhibitor of the androgen receptor (AR), CPIC, that would be effective in the treatment of...

Biosynthesis of Lantibiotics: In vitro semi-synthetic production methods for generation of industrial antibiotic, Lacticin 481

 

This invention allows the engineering of semi-synthetic lantibiotics to a much larger extent than using typically practiced in vivo methods. The method is the...

Ionizable Isotopic Labeling Reagents for Relative Quantification

 

Liquid chromatography/mass spectrometry (LC/MS) is increasingly being used for metabolic analysis due in part to its widespread availability and compatibility with...

Gene Cluster Capable of Enabling the Biosynthesis of the Antimicrobial Compound, Rhizocticin In Bacillus subtilis

 

Phosphonic and phosphinic acids are bioreactive compounds that have been used as antibiotics, antifungal agents, antimalarial drugs, and herbicides. Rhizocticins...

Lantibiotic Screening Technique

 

Dr. van der Donk has developed a screening system for identifying novel antibiotics. The system uses phage display and has been optimized for lantibiotic natural...

Preparation of Degradable Silica-Drug Conjugated Nanoparticle with Monodisperse Particle Sizes

 

The invention provides a silica nanoparticle comprising a non-porous matrix of silicon-oxygen bonds, wherein the matrix comprises organic agents conjugated to...

Therapeutic Agents for Treatment of Myotonic Dystrophy

 

Dr. Zimmerman's lab has developed a series of bioactive compounds for the treatment of myotonic dystrophy. The compounds disrupt the MBNL-(CUG) foci in vivo and...

Pharmaceutical Compounds and Pathways from Actinobacteria

 

Dr. Metcalf and Dr. van der Donk from the University of Illinois have discovered 12 novel phosphonate natural products as well as the genes responsible for the...

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