Small Molecules

Latest Innovations

Powerful Biphosophonates for Treatment of Cancer, Bone Loss, and Infectious Disease

 

Although there are already a few existing compounds for use in the treatment of bone diseases, these new compounds may have efficacy exceeding that of current...

Algorithm Modified Deoxynybomycin for the Treatment of Gram-Negative Bacteria

Dr. Hergenrother from the University of IL has developed a novel antibiotic that is effective against certain antibiotic-resistant gram-negative bacteria. His powerful...

A Pro-Apoptotic Microbial Community Network Enriched in the Tissue of IPF and Lung Cancer Patients

 

 

Dr. Isaac Cann from the University of Illinois has identified biomarkers and therapeutic strategy for treatment of...

Small Molecules With Antibacterial and Anticancer Activity

Dr. Hergenrother from the University of Illinois at Urbana-Champaign has developed a series of topoisomerase inhibiting small molecules...

PAC-1 combination therapy for Uveal Melanoma

Dr. Hergenrother from the University of Illinois at Urbana-Champaign has developed a new synergistic combination therapy using the small...

Ligand for Potential Treatment of Myotonic Dystrophy Type 1 (DM1)

Dr. Zimmerman from the University of Illinois at Urbana-Champaign has developed an oligomeric ligand that can have potential...

Novel Toll-Like Receptor Inhibitors for Treatment of Inflammatory Disease

Dr. Katzenellenbogen from the University of Illinois at Urbana-Champaign has developed a novel class of inhibitors capable of inhibiting Toll-like Receptor signaling....

Novel Endocannabinoid Therapeutics

Dr. Aditi Das from the University of Illinois at Urbana-Champaign has developed a novel set of therapeutic endocannabinoid derivatives....

Novel Estrogen Receptor β (ERβ) Drugs for the Treatment of Multiple Sclerosis (MS)

Currently available therapeutic agents approved for the treatment of multiple sclerosis (MS) reduce relapse rates, but do not reverse or prevent neurodegeneration nor...

In vivo Active Inhibitors of FOXM1 for the Treatment of Breast Cancer

Triple Negative Breast Cancer (TNBC) constitutes about 10-20% of all diagnosed breast cancers and is known to be more aggressive and difficult to treat. TNBC lacks the...

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