Small Molecules

Latest Innovations

Algorithm Modified Deoxynybomycin for the Treatment of Gram-Negative Bacteria

Dr. Hergenrother from the University of IL has developed a novel antibiotic that is effective against certain antibiotic-resistant gram-negative bacteria. His powerful...

A Pro-Apoptotic Microbial Community Network Enriched in the Tissue of IPF and Lung Cancer Patients

 

 

Dr. Isaac Cann from the University of Illinois has identified biomarkers and therapeutic strategy for treatment of...

Small Molecules With Antibacterial and Anticancer Activity

Dr. Hergenrother from the University of Illinois at Urbana-Champaign has developed a series of topoisomerase inhibiting small molecules...

Ligand for Potential Treatment of Myotonic Dystrophy Type 1 (DM1)

Dr. Zimmerman from the University of Illinois at Urbana-Champaign has developed an oligomeric ligand that can have potential...

Novel Endocannabinoid Therapeutics

Dr. Aditi Das from the University of Illinois at Urbana-Champaign has developed a novel set of therapeutic endocannabinoid derivatives....

In vivo Active Inhibitors of FOXM1 for the Treatment of Breast Cancer

Triple Negative Breast Cancer (TNBC) constitutes about 10-20% of all diagnosed breast cancers and is known to be more aggressive and difficult to treat. TNBC lacks the...

Novel Endocannabinoid Therapeutics

Therapeutic endocannabinoid derivatives showing an increased half-life and enhanced anti-migratory properties. These compounds retain the anti-inflammatory, anti-cancerous...

Dearomative carboamination and its application in synthesis of anticancer agents

New synthesis method for isocarbostyril alkaloids based on dearomative carboamination of the benzene ring. This is the shortest and most efficient method known to date,...

Converting Gram-Positive Antibiotics to Gram-Negative Bacteria

Dr. Hergenrother from the University of IL has developed a method to convert compounds of Gram-positive antibiotics to Gram-negative antibiotics. This method and...

Complex Compounds From the Natural Product Lycorine

Dr. Hergenrother from the University of Illinois has created a diverse compound screening library from the synthetic scaffold lycorine. Lycorine is an alkaloid isolated...

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