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Diagnostic Hardware/Software/Medical Devices

Latest Innovations
Computed Pathology: Stain-Free Computational Imaging Researchers from the University of Illinois have developed a method of stain-free chemical imaging to highlight the morphology and molecular content of biological... Read More Researchers from the University of Illinois have developed a method of stain-free chemical imaging to highlight the morphology and molecular content of biological samples without the use of any stains or dyes. The tissue is computationally recreated as if it were stained and imaged in diagnosis of biological samples. This method improves the cost and efficiency by avoiding expense and lessening the time required to complete multiple stains. Also, it improves the overall consistency of the staining process.
RF Coil for Improving Tuning Range, Cost and Maintaining Q A radio frequency (RF) coil comprising a plurality of electrically uninterrupted conductive legs, each leg having a first end and a second end, and at least one... Read More A radio frequency (RF) coil comprising a plurality of electrically uninterrupted conductive legs, each leg having a first end and a second end, and at least one continuous conductor electrically connected to the first ends of the legs. Frequency tuning of the coil is achieved by translating, along the legs, an electrically continuous tuning band that includes a capacitor closed about the axis of the coil in proximity to the conductive legs. Maintaining electrical symmetry of the coil results in tuning ranges of at least 30 percent of the nominal value of the resonant frequency.
Electronic Point of Care System for Detecting a Variety of Biomarkers Medical professionals need techniques that will help them diagnose diseases before debilitating symptoms begin to manifest in patients. Point of care testing, or... Read More Medical professionals need techniques that will help them diagnose diseases before debilitating symptoms begin to manifest in patients. Point of care testing, or bedside testing, enables rapid diagnostic tests to be performed at a patient's bedside. Benefits include: Immediate data, which can be interpreted by nurse or trained technician Decreased cost and effort, which could dramatically increase frequency of patient testing Cost-effective method to produce patient biomarker profile Dr. Bashir's lab has invented a label-free, electronic method for quantifying various biomarkers from blood. This method may be incorporated into a portable handheld device which enables healthcare professionals to perform complete blood count diagnostics at the point of patient care. Key advantages over existing competing technology include versatility, scalability, and decreased cost of production.
Project Multiband, Multishot Magnetic Resonance Elastography Pulse Sequence This is an imaging technique designed for estimating the stiffness of tissues non-invasively. This technology can be used to understand a wide array of... Read More This is an imaging technique designed for estimating the stiffness of tissues non-invasively. This technology can be used to understand a wide array of neurological disorders. This method has a significantly shorter scan time than previous methods disclosed by the same research group. A “speaker” is used to vibrate the brain and this acquisition software is fast enough to capture motion without blur. Using this multislab approach allows for short repetition time in MR scanning with a very high signal-to-noise ration (SNR). This allows for a whole-brain scan with 2mm isotropic spatial resolution in only 3 minutes. Benefits Uses multiband excitation 3D distributed slab encoding Non-linear phase error correction
In vivo Thickness Mapping of the Tympanic Membrane Dr. Stephen Boppart from has developed a new method of mapping the thickness of the tympanic membrane. This method uses LCI and video otoscopy data to... Read More Dr. Stephen Boppart from has developed a new method of mapping the thickness of the tympanic membrane. This method uses LCI and video otoscopy data to piece together a full image of the tympanic membrane and overlay that image with thickness measurements. This will allow physicians to noninvasively examine tympanic membrane thickness leading to more accurate and less invasive diagnose middle ear infections.
Point of Care Ocular Globe Injury Diagnostic Device Dr. Pan from the University of Illinois at Urbana-Champaign has developed a point of care device that can detect a penetrating ocular globe injury. Unlike current point of... Read More Dr. Pan from the University of Illinois at Urbana-Champaign has developed a point of care device that can detect a penetrating ocular globe injury. Unlike current point of care diagnostic tests for ocular globe injuries, which require a trained physician to subjectively identify a change in the color of a dye placed onto the ocular surface, the invention can be administered by a nurse or technician. This technology will allow for faster, cheaper, and more mobile means of diagnosing certain eye injuries.
Measuring Blood Vessel Characteristics of Suspected Alzheimer Patients Dr. Sutton has developed MRI protocols for diagnosing microvascular blood velocity and microvascular segment length. These protocols can be used to diagnose and track... Read More Dr. Sutton has developed MRI protocols for diagnosing microvascular blood velocity and microvascular segment length. These protocols can be used to diagnose and track Alzheimer's Disease and other neurological disorders. The protocols are capable of creating images of brain microvasculature at high resolution, and both the acquisition and image construction times are reasonable.
MRSI Improvements Dr. Liang from the University of Illinois at Urbana-Champaign has developed new MRI acquisition methods and post-acquisition data processing techniques that allow for a... Read More Dr. Liang from the University of Illinois at Urbana-Champaign has developed new MRI acquisition methods and post-acquisition data processing techniques that allow for a standard MRI instrument to perform traditional spin density imaging as well as susceptibility mapping, quantitative susceptibility mapping, and metabolite mapping with high resolution and signal to noise ratio from a single scan. Unlike other techniques, such as CT scans, the current technology does not require ionizing radiation and is thus safer for patients and radiology professionals.
A Machine Learning Approach to Elasticity Imaging Professor Insana from the University of Illinois at Urbana-Champaign has developed an information based technique to determine the... Read More Professor Insana from the University of Illinois at Urbana-Champaign has developed an information based technique to determine the mechanical properties of soft biological media. This technique has been adapted from the Auto-progressive algorithm that was originally developed for civil engineering applications. This algorithm is a unique combination of Force Displacement, Finite Element Algorithm (FEA), and Artificial Neural Network (ANN) along with what to sample and where to look. It is better than the inverse analysis or dynamic imaging techniques in that it has a machine learning aspect which eliminates the need of making any initial assumptions about the media being imaged. The technology has a lot of potential in non-linear imaging and is not tied to any one particular type of imaging technique. Its primary application is in ultrasound imaging.
Magnetic Resonance Spectroscopic Imaging of Brain DNA Methylation Drs. Li, Robinson, Liang, Silverman and Mr. Lam from the University of Illinois at Urbana-Champaign have developed a new noninvasive method of measuring epigenetic changes... Read More Drs. Li, Robinson, Liang, Silverman and Mr. Lam from the University of Illinois at Urbana-Champaign have developed a new noninvasive method of measuring epigenetic changes in a living human brain, specifically DNA methylation, which is related to memory formation. Its main application is diagnosis of Alzheimer’s disease and other neurological disorders. Exiting imaging techniques for Alzheimer’s diagnosis reveal only the presence of amyloid plaques. Even though amyloid plaques in the brain are a characteristic feature of Alzheimer's disease, their presence cannot be used to diagnose the disease. This new method allows tracking methylation in brain which is directly responsible for memory formation, and therefore it is a more accurate indicator of Alzheimer's disease. The method is noninvasive, and allows for a more flexible administration of the contrast medium.

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