Human Systems

Latest Innovations

In vivo Active Inhibitors of FOXM1 for the Treatment of Breast Cancer

Triple Negative Breast Cancer (TNBC) constitutes about 10-20% of all diagnosed breast cancers and is known to be more aggressive and difficult to treat. TNBC lacks the...

Novel Class of Anti-estrogen Drugs for the Treatment of Breast Cancer

Many estrogen receptor α (ERα)-positive breast cancers often develop resistance to endocrine therapy due to mutations in ERs. These mutations are associated with shorter...

Novel Endocannabinoid Therapeutics

Therapeutic endocannabinoid derivatives showing an increased half-life and enhanced anti-migratory properties. These compounds retain the anti-inflammatory, anti-cancerous...

Dearomative carboamination and its application in synthesis of anticancer agents

New synthesis method for isocarbostyril alkaloids based on dearomative carboamination of the benzene ring. This is the shortest and most efficient method known to date,...

Large Scale Parallel DNA Detection by 2D Solid-state Multi-pore Systems

A scalable device design of a dense array of multiple 2D nanopores made from nanoscale semiconductor materials to simultaneously detect multiple DNA strands and identify...

Solution Coating and Printing of Pharmaceutical Nanothin Films and Multilayer Nanocomposites

A meniscus-guided solution coating technique to produce pharmaceutical nanothin films. This is a new way to manufacture personalized multilayer combination drugs, which...

Novel Estrogren Receptor β (ERβ) Drugs for the Treatment of Endometriosis

Endometriosis is the growth of endometrial lesions outside of the uterus – these lesions are adherent on various organs in the peritoneum, including the ovaries. It is a...

Novel Toll-like Receptor Inhibitors for the Treatment of Inflammatory Diseases

Toll-like receptors (TLRs) have been shown to play a vital role in the pathogenesis of many diseases, including inflammatory diseases. Exaggerated or prolonged TLR...

Robotic Surgery with Haptic Feedback

Researchers from University of Illinois have advanced the field of robotic surgery by introducing haptic feedback based on the 3D point cloud reconstruction technique. The...

Detection of Neurotransmitters via Interfacial pH Modulated Assisted Ion Transfer

Dr. Shen from University of IL has developed an electrochemical method to directly detect neurotransmitters gamma-aminobutyric acid (GABA) and glutamate without...

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