Single-chip Neural Probe with High Temporal Resolution

Dr. Yurii Vlasov from the University of Illinois has developed a single-chip neural nanodialysis probe that can sample in vivo brain chemicals, store them, and then directly deploy them for analysis, all while maintaining high temporal resolution.

This device uses reversible inlets-outlets and embedded ionization ports to both sample in vivo brain chemicals and deploy them, without need for intermediate storage. This risks less contamination or Taylor dispersion than other methods, and reduces the need for bulky peripherals.

 

Application

This can be used for collecting and analyzing in-vivo biochemical concentrations in the brain. 

Benefits

This is a single chip silicon neural probe that can sample live chemicals, store them, and then directly deploy them for analysis. Other neural probes cannot store and deploy these chemical samples, which reduces the temporal resolution of the samples.