Solution Coating and Printing of Pharmaceutical Nanothin Films and Multilayer Nanocomposites

A meniscus-guided solution coating technique to produce pharmaceutical nanothin films. This is a new way to manufacture personalized multilayer combination drugs, which can be beneficial to types of cancer where mono-chemotherapy is ineffective. This new technology enables a uniform deposition of thin films down to a few nm in thickness, easy alternation of the film morphology (modulation of dissolution rate) and polymorphism (control of bioavailability), and a layer-by-layer production of dosages comprised of multiple active pharmaceutical ingredients. The method is cost-competitive, scalable, and high-throughput.