Nanomaterial for Active Release of Molecules in Response to Increase in Internal Pressure 

Dr. Hyunjoon Kong from the University of IL has developed a MnO2 based nanosheets complexed with alginate encapsulated in PLGA. This formulation can be used for active release of molecules that uses internal pressure as a trigger in response to H2O2 exposure.
This invention is a composition of matter that can be used as a method in drug delivery. The nanomaterial releases O2 gas in response to H2O2. This results in an increase in internal pressure and subsequent release of the active molecule. The advantage of this system is that it can be used for targeted delivery of active molecules at a controlled rate. This technology has application in theranostics as well as food industry.