Unprecedented control of cofactor regeneration using Microfluidic Device that Performs Electrochemical Synthetic Reactions
This microfluidic device is an electrochemical cell based on multi-stream laminar flow. It allows for specific control over reactions taking place at the electrodes. For example, the regeneration of cofactors that are important for biocatalysis can be performed at good conversion efficiencies in this microfluidic device, whereas cofactor regeneration according to the same principle is impossible at the macroscale. A dynamic membrane is generated inside microchannels as a result of the multi-stream laminar flow to provide this new ability for control. Graphite plates or other conductive materials can serve in combination of any or all of the purposes of (i) catalyst support structure; (ii) the material that provides in part the dimensions of the microfluidic channel structure through which the reactants flow; and (iii) the collector of the current resulting from the electrochemical process taking place on the electrodes.