Dr. Rashid Bashir has developed a novel method for spatial gene analysis that removes the need for purification and homogenizing steps typical in RNA amplification techniques. This method combines microfabrication and bioengineering in a unique manner that allows for spatial gene analysis in 2 hours or less. The method uses a chip patterned with thousands of picoliter microwells with sharp edges that pixelate the tissue without cross contamination. This preserves spatial data and allows amplification in each microwell.