Existing delivery systems have many limitations related to efficiency and safety. Some of these techniques include the gene gun, high voltage electroporation, lipofection, infective viruses (i.e. retroviruses, herpes and adenoviruses) or bacteria. An ideal molecular delivery system should be safe, highly efficient, biocompatible, non-immunogenic, capable of protecting DNA/RNA/protein, and small in size. The majority of existing delivery systems are used for in vitro transfection and have low efficiencies (i.e.