Technologies

Gene and Cell Therapy

Decitabine is used for cancer treatment and other hematological disorders. The UIC inventors have developed a novel formulation of Decitabine. This formulation has improved oral absorption, decreased inter-individual variability, and improved efficacy against cancer cell resistance.
There are a number of options for the replacement of missing teeth.  Dental implants and implant-supported bridges are available as permanent solutions and removable dentures and dental bridges are common non-surgical treatment options.  Implants have the benefit of strength and durability and can be used along with bridges or independently.  They also generally do not necessitate any alterantion to the shape of the surrounding teeth.  It has been shown that people with implants eat better and are healthier and enjoy life more than people with dentures.
Gene therapy is an approach for human disease treatment. This is done by inserting nucleic acids into cells to produce proteins, fix or replace damaged genes, and inhibit expression of harmful genes. The gene delivery systems are classified into viral and nonviral systems.  There are several advantages in nonviral delivery systems, including biological safety (safer than viral vehicle), low immunogenicity, ability to deliver large genes, and large scale production at a reasonable cost.
Cancer is one of the leading causes of death throughout the world. Curing cancer has been a major goal of medical researchers for decades, but development of new treatments takes time and money. Recent knowledge on apoptosis has made it possible to devisenovel approaches which exploit this process of cancer treatment. Furthermore, the majority of chemotherapeutic agents as well as radiation utilize the apoptotic pathway to induce cancer cell death.
Hepatocellular Carcinoma (HCC), also known as primary liver cancer or hepatoma, is a cancer that ari
The present invention is a medical invention related to a novel therapeutic strategy for the treatment of pulmonary hypertension. Pulmonary hypertension is continuous high blood pressure in the pulmonary (lung) artery, and may be either primary (unknown etiology), or secondary (due to chronic heart or lung disease, blood clots in the lungs, or scleroderma). Current treatment protocols for pulmonary hypertension are often complex and require multiple combination drug regimens in addition to extensive follow-up care.
Currently there are no vaccines or treatments that prevent Herpers Simplex Virus-1 (HSV-1). The inventor has identified specific peptides to heparan sulfate that could possibly be a prophylactic or therapeutic agent against Herpes infection. The peptide blocks Herpes Simplex Virus –1 from entering cells.
This technology is a short fragment of a naturally occurring peptide that can be used to regulate the density of calcium current in mammalian cells. Modulation of calcium current across cell membrane
This technology marries the Recombinant Human Tissue Factor (TF) with Membrane Scaffold Protein (MSP) NanodiscsTM, resulting in an efficient and easy to administer blood c
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