Technologies

Cellular Engineering

HSD17B7 construct for the generation of HSD17B7 knockout mice.
Periodontal disease is one of the major reasons for tooth loss in the United States and may be associated with systemic effects, including heart disease and rheumatoid arthritis. Although tooth retention has greatly improved over the past few decades, a significant percentage of older Americans do not have functional dentitions and only 42.4% of the U.S.
Loss of dental and craniofacial tissues due to disease, injury or genetic disorders negatively affects the quality of life of millions of Americans. Presently, the gold standard in clinical treatment for craniofacial bone defects is autografts and demineralized bone matrix (DBM). Autografts perform exceptionally well, but are known to induce donor site morbidity and DBMs poorly induce regeneration of lost tissue.
Improving the efficacy of cystic fibrosis treatments remains a challenging goal with many potential solutions.
The present invention provides a versatile microrod-Matrigel composite system that can modulate the local microenvironment of ce
Researchers at the University of Illinois have developed a family of novel, synthetic nucleoside analog inhibitors of viral reverse transcriptase (RT) that could potentially offer new treatment option
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