University and Sigma-Aldrich Announce Licensing Agreement to Expand Range of Powerful Building Blocks for Small Molecule Synthesis
Urbana, IL– University of Illinois at Urbana-Champaign and Sigma-Aldrich® have entered into a licensing agreement which enables Sigma-Aldrich to expand the range of a powerful class of boronic acid surrogates offered to the global chemistry community. Boronic acids are building blocks for Suzuki-Miyaura cross-couplings, one of the most widely used chemical reactionsto form carbon-carbon bonds.
The University of Illinois and MEMSIC Enter Agreement to Add Structural Health Monitoring Capabilities to Wireless Sensor Platform
MILPITAS, Calif., July 29, 2010 (BUSINESS WIRE) -- Building on its popular Imote2 advanced wireless sensor platform, MEMSIC, Inc. (NASDAQGM: MEMS) announced today the new Imote2 Structural Health Monitoring Board(ISM400), an integrated sensor board that enables an inexpensive means for continuous and reliable Structural Health Monitoring (SHM) using dense arrays of wireless smart sensors.
Accuratelymodeling detonation shock fronts is a critical challenge for explosiveengineers in aerospace, defense, mining, drilling, and demolition. Currently available level set-based modelsuse a computationally intensive process to model every point on a definedplane, resulting in extreme accuracy at speeds so slow that many users neverrun high resolution models at all. Particle-based models run more quickly, but are difficult to implementand likely to miss splits and merges in the wave front.
Identification and Analysis of Genes Necessary for the Biosynthesis of the Phosphonate Antibiotic Dehydrophos from Streptomyces luidus
Bacterialresistance to antibiotics is a growing problem. Phophonic and phosphinic acids are compounds with a carbon-phosphorusbond with P in the reduced form. They sharestructural similarity with phosphate esters and carboxyalte-containingcompounds which are ubiquitous metabolites in cellular biology, making themless toxic to the host organism. Inaddition, because these compounds exist in a reduced form, these compounds arehighly resistant to hydrolysis and enzymatic cleavage, making them morestable.
Cancer researchers are focusing their efforts on identifying central pathways that trigger or enhance the invasiveness of tumor cells. One such target is EMMPRIN (Extracellular Matrix Metalloproteinase Inducer). It has been shown that EMMPRIN expression is linked to various cell signaling pathways that lead to an increase in tumor cell vascularization. Researchers are focusing efforts on elucidating the role of EMMPRIN in a number of disorders including cancer, arthritis, tissue repair and numerous inflammation-dependent diseases.
Advanced molecular imaging tools combinedwith investigative tools like biochemical and cell based assays have thepotential to unravel complex molecular processes. These tools combined withhigh throughput screening can significantly impact diagnostics for cancerscreening and accelerate drug discovery. The present inventions are two new FluorescenceResonance Energy Transfer (FRET) biosensor pairs, one composed of two newcolors, mOrange2 and mCherry and the other composed of a modified high-sensitiveECFP/YPet pair that can significantly enhance the dynamic range of a variety ofbiosensors.
Domestic soybean cultivars used in the U.S. are highlysusceptible to soybean rust disease caused by Phakopsora pachyrhizi. The rapid spread of the disease and its abilityto cause significant yield losses (ranging from 13 to 80% of total yield) canresult in major economic losses for soybean producers. Synthetic fungicides areheavily used (~74 million acres in US in 2007) to prevent rust disease buttheir effect on human health and the ecosystem is unknown.
Strategiesfor bio-integrated electronics must overcome the numerous challenges associatedwith the mismatch between the hard, planar surfaces of semiconductor wafers andthe soft, curvilinear tissues of biological systems. These differences between the surfaces leadto low fidelity coupling at the biotic/abiotic interface as well as limitedlong-term tissue health. Even extremelythin, flexible systems can only wrap around shapes with zero Gaussian curvature(such as developable surfaces such as cones and cylinders).
Soybean aphid is an invasive insect pest that was first discovered in North America in 2000. Since then, these aphids have become a significant pest in the soybean producing regions of the northern USA and southern Canada. Currently, millions of acres of fields are sprayed with insecticide each year, which is both costly and has potential environmental implications. Researchers at the University of Illinois and USDA – Agricultural Research Service have identified a gene that can confer aphid resistance for soybeans.
Each year our new class of interns shows off their culinary chops at our cooking challenge, and we enjoy the delicious results.
Here are some of the best recipes
Fruited Ice Cream Cake (best when it stays frozen) ½ gallon vanilla ice cream (From Michael Hodnett, intern 2009-2011)
4 ½ cups sliced strawberries
1 box Danish dessert (Junket brand)
2 ½ cups ricecrispies
1 cup chopped walnuts
1 cup grated coconut
1 cup brown sugar
1 cube margarine
1 Tbsp corn syrup
Heat margarine, brown sugar and corn syrup until sugardissolves. Add rice crispy, coconut, andchopped walnuts. Mix well.
Press half of rice crispy mixture onto the bottom of a 9x 13 pan. Beat ice cream with a mixeruntil you can spread it on top of the layer of the rice crispy mixture. Sprinkle the other half of the mixture on topof ice cream. Freeze.
Follow directions on Danish dessert for fruit sauce,adding chopped strawberries. Chill. Drip sauce over frozen cake before serving.
Thai Chicken Pizza (from Kyle Beckemeyer, intern 2010-2011)
1 pizza crust – (I used Boboli regular crust)
¾ cup thai peanut sauce
1/6 cup peanut butter
1 Tablespoon of soy sauce
1-2 cups shredded chicken (already cooked chicken)
1-2 cups of mozzarella cheese
1 Red pepper
• Preheat the oven to 400 degrees F (200 degrees C).
• In a small bowl, stir together the peanut sauce, soy sauce, and peanut butter. Spread over the
pizza crust. Arrange strips of chicken on top. Sprinkle on the green onions, red peppers,
• Bake for 8 to 12 minutes, until cheese is melted and bubbly.
• Top with bean sprouts, carrot shreds and cilanto; you are ready to serve!
Strawberry Cheesecake Trifle (from Jennifer Schmidt, intern 2010-2011)
Adapted from Cooks.com
Serves 10 to 15
2 (8 oz.) pkgs. cream cheese
1 (8 oz.) carton sour cream
1 pt. whipping cream
2 c. confectioners' sugar
1 vanilla bean + ½ tsp. vanilla extract (may substitute 2 tsp. vanilla extract)
1 lg. angel food cake
2 lb. sliced strawberries (this amount can be varied)
3 Tbsp. sugar, optional
- Beat cream cheese until it is softened. Beat in sour cream. (Using room temperature cream cheese and sour cream make it easier to blend together.)
- In another bowl, beat whipping cream until soft peaks form.
- Stir into creamed cheese mixture.
- Stir in confectioners' sugar and vanilla.
- Cut angel food cake into ½-inch slices.
- Sugar berries with 3 Tbsp. sugar, if desired.
- Using deep glass bowl, creamed mixture, angel food cake and strawberries, beginning and ending with creamed mixture. Garnish top as desired.