Therapeutics

Latest Innovations

Therapeutic Scheme for Human Basigin

 

Cancer researchers are focusing their efforts on identifying central pathways that trigger or enhance the invasiveness of tumor cells. One such target is EMMPRIN (...

New Drugs for Malarial and Bacterial Infections

 

New anti-infectives are required now more than ever as resistance to existing drugs increases in prevalence. Enzymes unique to bacteria or parasites are potential...

Gene Cluster Capable of Enabling the Biosynthesis of the Antimicrobial Compound, Rhizocticin In Bacillus subtilis

 

Phosphonic and phosphinic acids are bioreactive compounds that have been used as antibiotics, antifungal agents, antimalarial drugs, and herbicides. Rhizocticins...

Supramolecular Assembly for Non-Viral Gene Delivery

 

Gene therapy is an approach for human disease treatment. This is done by inserting nucleic acids into cells to produce proteins, fix or replace damaged genes, and...

Genes for the Biosynthesis of Plantazolicin, a Molecule Effective in Killing Bacillus Anthracis

 

Anthrax disease, caused the by the bacterium Bacillus anthracis, is a major bioterrorism threat. Currently, B. anthracis infections are treated with various broad-...

Electronic Tuning Of Site Selectivity For Complex Molecule Synthesis

 

Researchers from the University of Illinois have developed a method for selectively derivatizing complex natural molecules such as Amphotericin B. The technology...

Antibacterial Drug Targeting Isoprenoid Biosynthesis

 

Researchers at the University of Illinois and the University of California at San Diego have developed a variety of potential inhibitors of Isoprenoid biosynthesis...

Less Toxic Amphotericin B Derivative

 

Researchers at the University of Illinois have developed a derivative of Amphotericin B that likely has a lower toxicity than the popular fungicide. The derivative...

Compounds for the Treatment of Fluoquinolone resistant infections

 

Researchers from the University of Illinois have synthesized a variety of compounds with strong activity toward fluoroquinolone resistant bacteria. These compounds...

A Novel Treatment for Fragile X Synaptic and Cognitive Deficits

Fragile X syndrome (FX) is the most common form of inherited intellectual disability and occurs in roughly 1:3,600 males and 1:8,000 females. Physical features associated...

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