Disease Type

Latest Innovations

Multi-Functional Plasmon-Resonant Contrast Agents for Optical Coherence Tomography (OCT)

 

This portfolio of optical contrast agents and molecular detection technologies were developed to enhance the ability of optical coherence tomography (OCT) to non-...

Compounds that Selectively Induce Cancerous Cell Death in the G1 Phase of the Cell Cycle

 

Malignant melanoma is a cancer that is refractory to current chemotherapeutic treatments. Through the synthesis of a combinatorial library of potential...

Biosynthesis of Lantibiotics: In vitro semi-synthetic production methods for generation of industrial antibiotic, Lacticin 481

 

This invention allows the engineering of semi-synthetic lantibiotics to a much larger extent than using typically practiced in vivo methods. The method is the...

Tissue Factor (TF) Nanodisc

 

This technology marries the Recombinant Human Tissue Factor (TF) with Membrane Scaffold Protein (MSP) Nanodiscs, resulting in an efficient and easy to administer...

Compounds That Selectively Induce Cancerous Cell Death in the G1 Phase of the Cell Cycle

 

Malignant melanoma is a cancer that is refractory to current chemotherapeutic treatments. The average survival time for patients is 6 months. This coupled with the...

Powerful Biphosophonates for Treatment of Cancer, Bone Loss, and Infectious Disease

 

Although there are already a few existing compounds for use in the treatment of bone diseases, these new compounds may have efficacy exceeding that of current...

Peptide Based Inhibitor of Calcium Current

 

This technology is a short fragment of a naturally occurring peptide that can be used to regulate the density of calcium current in mammalian cells. Modulation of...

Lanthanide Chelate

 

Lanthanide chelates derived from diazacrown ethers having two ethyliminodiacetic acid side chains have increased ability to bind lanthanide ions.

Controlled Targets-Specific Drug Delivery via DNAzyme (aptazyme or aptamer) - Functionalized Liposome

 

An amphiphilic substance includes a hydrophobic group, and a polynucleotide group attached to the hydrophobic group. The polynucleotide group includes a first...

A More Stable and Efficient Retroviral Gene Delivery Vector

 

This technology is a viral vector based on the murine leukemia virus (MLV), which has been favored for clinical gene therapy due to its preferential infectivity of...

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