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A Handbook for Inventors and Innovators: Technology Transfer at the University of Illinois

An introduction to the University’s intellectual property policies, patenting and commercialization services, intellectual property fundamentals, and most importantly, to your role in the process of commercializing University innovations. Learn more.

Latest Technologies

Histone deacetylases (HDACs) mediate regulation of gene expression via changes in nucleosome conformation.  Dysregulation of histone acetylation, can lead to the development of cancers. There is renewed interest in capitalizing new breakthroughs in epigenetic research to address oncology therapy. Epigenetic regulation and subsequent gene expression or silencing represents a tightly orchestrated interplay among enzymes responsible for modifying the tails of histones, around which nuclear DNA is wrapped.
Histone deacetylases (HDACs) mediate regulation of gene expression via changes in nucleosome conformation.  Dysregulation of histone acetylation, involving CBP, a neuroprotective transcription factor with histone acetyltransferase activity, has been found in Huntington’s disease (HD), Alzheimer’s disease (AD), and Rubinstein-Taybi syndrome. In a cellular model of AD, cell death was accompanied by loss of CBP function and histone deacetylation. 
G9a is overexpressed in various human cancer including leukemia, prostate cancer, hepatocellular carcinoma and lung cancer. Inhibitors of G9a are candidates for cancer treatment. A new family of G9A inhibitors have been recently identified and characterized. Through the characterization of these inhibitors, insight has been gained on the mechanistic contribution of G9a in the deregulation of the cell cycle in cancer and methyltransferase G9a regulation of a crucial step in cellular degradation.
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One Llama Media, Inc.

One Llama Media develops software filtering and navigation tools for music and video with acoustic and cultural analysis. The company has a team of music analysts from the International Music Information Retrieval Systems Evaluation Laboratory (IMIRSEL) project at the University of Illinois.

Business Logic Corporation

Finance tools to help financial industry customers understand, organize, and manage investments.

Illumia

Dr. Terry von Thaden, Institute of Aviation and the Graduate School of Library and Information Science, combines principles from information science and human factors to provide safety culture measurment services and training recommendations to commercial aviation operators.

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